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Abstract
Discussion Forum (0)
Introduction:
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
Introduction:
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
The Effect of Co-Existing Maternal Obesity and Chronic Hypertension on Neonatal Birth Weight
Elizabeth Pinkerton
Abstract
Discussion Forum (0)
Introduction:
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
Introduction:
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
While the individual effects of maternal obesity and chronic hypertension on neonatal birthweight are well known, there is little data when these factors are co-existing. The goal of this study was to investigate the effect of these co-existing factors on neonatal birthweight.
Methods:
This retrospective cohort study utilized the 2018 CDC Natality Database. IRB approval was obtained. Live birth records at 37, 38, and 39 weeks with recorded birthweight and maternal BMI greater than 18.4 were isolated. Exclusion criteria included maternal pregestational or gestational diabetes, gestational hypertension, preeclampsia, eclampsia, maternal tobacco use, multi-gestational pregnancies, suspected or confirmed chromosome disorder, or fetal anomaly.
Results:
Univariate analysis of the primary objective revealed that neonates born from mothers with obesity and chronic hypertension weighed more than mothers without by 17g, 28g, and 18g at 37, 38, and 39 weeks respectively. The secondary objective compared birthweights at varying obesity levels. At the same maternal BMI, neonates born from mothers with hypertension weighed less than those without. Compared to normotensive, normal BMI mothers, neonates born from mothers with hypertension weighed less when maternal BMI was less than 30; weighed most similar at BMI 30-34.9; and weighed more as BMI increased over 35.
Conclusion/Implications:
While statistically significant differences in birthweight were noted between neonates from normotensive, normal BMI mothers and those with chronic hypertension and obesity, these differences of less than 50g are unlikely clinically significant. The opposing weight effects of obesity and hypertension balanced at BMI 30-34.9. Neonatal outcomes from mothers with co-existing risk factors should be investigated.
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