Abstract
Discussion Forum (0)
Introduction: Compare antepartum admissions and outcomes in pregnancies complicated by renal transplant (RT) versus chronic kidney disease (CKD).
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Introduction: Compare antepartum admissions and outcomes in pregnancies complicated by renal transplant (RT) versus chronic kidney disease (CKD).
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Obstetric Outcomes in Pregnancies Complicated by Prior Renal Transplant or Chronic Kidney Disease
Dr. Jessica Morgan
Abstract
Discussion Forum (0)
Introduction: Compare antepartum admissions and outcomes in pregnancies complicated by renal transplant (RT) versus chronic kidney disease (CKD).
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Introduction: Compare antepartum admissions and outcomes in pregnancies complicated by renal transplant (RT) versus chronic kidney disease (CKD).
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
Methods: Retrospective cohort study at University of Illinois at Chicago from 2010 to 2019. Electronic medical record queried for women age 18 to 51 with pregnancy, RT or CKD. SPSS used for statistical analysis. IRB approval was obtained.
Results: 577 charts reviewed, 57 pregnancies complicated by RT or CKD. Of 33 women with RT, 20 had live births, 11 miscarried, 2 had elective terminations. Of 24 women with CKD, 14 had live births, 6 miscarried, 2 had ectopic pregnancies, 2 had elective terminations. Average time from RT to pregnancy was 7.45 years. Subjects with CKD had higher rates of preterm delivery and hypertensive disorders of pregnancy. No difference in rate of cesarean delivery (CD) between groups. Gestational age (GA) at delivery lower in women with CKD than RT, 31 vs 34 weeks. Rate of antepartum admission not statistically significant between groups. Subjects with RT admitted for obstetric complications compared to women with CKD admitted for worsening medical problems. Pregnancies 1 to 3 years posttransplant had lower rates of preeclampsia and CD, and later GA at delivery (36.3 vs 34.4 weeks) compared to those greater than 3 years posttransplant.
Conclusion/Implications: Women with RT are not admitted antepartum at a higher rate than women with CKD and overall had better obstetrical outcomes. An area of further study is the ideal time between transplant and pregnancy, as we found improved obstetric outcomes in women with pregnancy closer to RT.
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