Unexplained Infertility: A Biomarker for Decreased Ovarian Reserve in Young Women
ACOG ePoster. Starostanko A. Apr 27, 2018; 212141
Dr. Andrea Starostanko
Dr. Andrea Starostanko
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Abstract
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Introduction: After 12 months of regular intercourse and appropriate evaluation to assure normal ovulation and sperm quality with patent fallopian tubes, no etiology is identified in up to 1/3 of couples. The treatment for Unexplained Infertility (UI), especially for younger couples (12 months attempting pregnancy.

Methods: Three hundred and forty-three nulligravid couples (18-34 yrs) were evaluated with assessment of tubal patency, ovulatory and anatomic status by mid-cycle TVUS, comprehensive semen analysis, and assessment of DOR with serum AMH.

Results: An infertility diagnosis was confirmed in 142/343 (41%): anovulation 30%; anatomic abnormality 9%; male factor 6%. UI, the default diagnosis, was made in 201/343 (59%). Of the 201 women with UI, AMH was
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