Behcet's Disease and Pregnancy: Obstetrical and Neonatal Outcomes in a Cohort of 12 Million Births
ACOG ePoster. Lee S. Apr 27, 2018; 212058; 34N
Seohyuk Lee
Seohyuk Lee
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Abstract
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Introduction: Behcet's disease (BD) is a rare inflammatory disorder for which limited and contradicting data exists in the context of pregnancy. This study aimed to estimate the prevalence of BD in pregnancy and to evaluate the associated maternal and fetal outcomes.

Methods: Using data collected by the Healthcare Cost and Utilization Project Nationwide Inpatient Sample from the United States between 1999 and 2013, we performed a population-based retrospective cohort study consisting of deliveries that occurred during this time period. ICD-9 codes were used to identify deliveries underwent by women with and without BD. We calculated the prevalence of BD in pregnancy and conducted multivariate logistic regression to estimate the adjusted effects of BD on maternal and fetal outcomes.

Results: We found an overall prevalence of 1.14 cases per 100,000 births between 1999 and 2013, rising from 0.5 to 2.4 per 100,000 births over the 14-year study period. Women with BD demonstrated a more than two-fold greater chance of being admitted to a hospital during pregnancy (p
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