Neonatal Outcomes After Hypertension in Twin Gestations: Potentially Protective?
ACOG ePoster. Roberts N. Apr 27, 2018; 212027; 29R
Nicole Roberts
Nicole Roberts
Login now to access Regular content available to all registered users.

You may also access this content "anytime, anywhere" with the Free MULTILEARNING App for iOS and Android
Abstract
Rate & Comment (0)
Introduction: To investigate whether and in what way neonatal outcomes vary in twin pregnancies affected by hypertension as compared with non-hypertensive twin pregnancies.

Methods: This was a retrospective cohort study of 1276 twin infants divided into four groups: non-hypertensives, chronic hypertensives, hypertensives developed during pregnancy without prior hypertension, prior hypertensives who developed pre-eclampsia in pregnancy. Outcomes assessed included gestational age at delivery, composite neonatal outcome, small for gestational age at less than the tenth percentile, 5 minute APGAR, and absolute birthweight.

Results: Chronic hypertensives were more likely to deliver prior to 34 weeks than non-hypertensives (OR 3.473; P=0.024) and were about 2.8 times more likely to have a low APGAR score (p = 0.0097) than women without hypertension. Women who developed hypertension in pregnancy were less likely than non-hypertensives to have one of the composite outcomes prior to adjustment (OR 0.6; p=0.008). This trend remained after adjustment for demographic variables but was not statistically significant (OR 0.679; p=0.090). Similarly, children of these women were less likely to have RDS (OR 0.89; p=0.025) prior to adjustment. Again, this became statistically non-significant after adjustment for demographic variation (OR 1.04; p=0.242).

Conclusion/Implications: This study supports some trends toward improved neonatal outcomes with hypertensive disorders developed in pregnancy as compared with non-hypertensive twin pregnancies and poorer outcomes of chronic hypertensive relative to non-hypertensive twin gestations. Prospectively collected data allowing for differentiation between gestational hypertension and pre-eclampsia with severe features would help further clarify these findings..
    This eLearning portal is powered by:
    This eLearning portal is powered by MULTIEPORTAL
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.


Save Settings