Breast Cancer in Pregnancy: A Retrospective Cohort Study
ACOG ePoster. D'Souza R. Apr 27, 2018; 211994; 24L
Rohan D'Souza
Rohan D'Souza
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Abstract
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Introduction: Our objective is to report pregnancy outcomes and placental histopathologic findings in women with breast cancer.

Methods: We conducted a retrospective study including pregnant women with a prior history of breast cancer and those with gestational breast cancer (GBC) managed at Mount Sinai Hospital, Toronto, Canada between 2004-2015.

Results: We identified 69 patients - 47 with a prior history of breast cancer and 22 with GBC. In 21/22 cases of GBC, treatment was initiated antepartum [surgeries in 16, mean gestational age (GA) 22.5 weeks and chemotherapy in 13 (mean GA 26 weeks). Radiotherapy was deferred until the postpartum period. There was a significant difference between groups in terms of labor induction (32.6 vs. 50%, p=0.045) to facilitate treatment, resulting in higher preterm birth rates (8.7% vs. 63.6%, p
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