Pregnancy Success via Intrauterine Insemination and Effect of Sperm Morphology: Systematic Review & Meta-Analysis
ACOG ePoster. Kohn J. Apr 27, 2018; 211918; 10E
Jaden Kohn
Jaden Kohn
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Introduction: Couples in which the man has abnormal sperm morphology are often counseled that natural conception and intrauterine insemination are ineffective and that in vitro fertilization is the only option. Our objective is to determine the effect of sperm morphology on pregnancy success using intrauterine insemination (IUI).

Methods: We systematically searched for studies published prior to January 2017 that 1) reported ultrasound-verified clinical pregnancies per IUI cycle; 2) assessed sperm morphology using the Kruger Strict Criteria; and 3) reported morphology at the 4% and ≤4% and/or ≥1% and 4% and ≤4%, the rate of ultrasound-verified pregnancy per cycle of IUI was not statistically or clinically different (14.2% vs. 12.1%, p=0.06) and the risk difference was 3.0% (95% CI 1.4–4.6%), indicating three additional pregnancies per 100 IUI cycles. Comparing men with ≥1% and
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